Clin2
NCT07531940Possibly a fitNot yet recruiting

Memantine for down syndrome

Down SyndromeIntellectual DisabilityAlzheimer Dementia (AD)

Treatments studied

Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.

This study tests whether a drug called memantine can help people with Down syndrome. It aims to see if it's safe and if it improves memory or thinking.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
25 people
Ages
18 years to 32 years
Study type
Interventional

Who can take part

  • You have Down syndrome (trisomy 21 or complete translocation).
  • You are at least 40 kg (about 88 pounds).
  • You are in good general health and can swallow pills.
  • You have a caregiver who can come to visits and help with medication.
  • You have not taken certain drugs (like amantadine, ketamine, or dextromethorphan) in the last 30 days.
  • You do not have other major psychiatric or neurological conditions (like autism, schizophrenia, or seizures in the last 3 years).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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