Testing Memantine Doses in Down Syndrome
Treatments studied
Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.
This study tests whether a medicine called memantine (already used for memory problems) can help people with Down syndrome think and remember better. Researchers will try different doses to find what works best and is safest.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Down syndrome caused by trisomy 21 (three copies of chromosome 21) confirmed by a genetic test
- You weigh at least 40 kg (about 88 pounds)
- You're in generally good health with no other major brain or mental health conditions besides Down syndrome
- You can swallow pills and have a reliable caregiver who can attend all visits with you
- Your heart rhythm is normal or has only minor, harmless abnormalities on an EKG
- You're not pregnant and willing to use reliable birth control if you could become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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