Cizutamig for generalized myasthenia gravis
Treatments studied
Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.
This trial tests an investigational drug called cizutamig for people with generalized myasthenia gravis (gMG) whose symptoms are not well controlled by current treatments. The goal is to see if it can improve daily activities.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with generalized myasthenia gravis (gMG) that is moderate to severe and does not require help breathing.
- Your MG symptoms affect daily life, with a score of at least 5 on a standard questionnaire, and at least half of the problems come from non-eye symptoms.
- Standard treatments like steroids or immune-suppressing drugs have not worked well enough, or there are no other effective options for you.
- You have not had a previous treatment called CAR-T or a T-cell engager (TCE) targeting any antigen or BCMA-targeted therapy.
- You do not have a history of certain immune system problems or serious medical conditions like poorly controlled diabetes, advanced kidney disease, or severe lung disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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