Liquid biopsy during spine surgery with blood-brain barrier disruption
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a technique called 'barrier disrupting fields' during spine surgery to temporarily open the blood-brain barrier. This may allow doctors to collect a liquid biopsy (a blood test that looks for tumor DNA) to better understand spinal tumors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are scheduled for spine surgery to remove a tumor inside the spinal cord covering (intradural)
- Your surgery will use brain and spine monitoring (neuromonitoring)
- You do not have a pacemaker or other implanted electrical device
- You are not pregnant or breastfeeding
- You are not taking blood thinners (anticoagulants)
- You have not had a skull fracture or brain surgery before
- You do not have a history of seizures or epilepsy
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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