Liquid biopsy guided brain treatment for advanced cancers
Part of Brain & nervous system, Cancer, Lungs & breathing, Skin clinical trials.
This study looks at using a liquid biopsy (a simple test on spinal fluid) to find cancer DNA in the fluid around the brain and spine. The goal is to see if this test can guide more targeted treatment for cancers that have spread to the central nervous system.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 years or older
- Have one of these cancers: HER2-positive breast cancer, triple-negative breast cancer, stage IV non-small cell lung cancer, or recurrent high-grade glioma
- Be scheduled for a spinal tap or have an existing spinal fluid access device as part of your regular care
- Have cancer DNA or abnormal cells found in your spinal fluid, as shown by a test
- Be under the care of a neuro-oncology team that agrees you might benefit from central nervous system-directed treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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