Clin2
NCT07224763Possibly a fitRecruiting

Pig kidney transplant trial for kidney failure patients

ESRD (End-Stage Renal Disease)Kidney TransplantationXenotransplantation

Part of Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests a genetically modified pig kidney (Thymokidney) for people with end-stage kidney disease who are on dialysis. It aims to see if this new type of transplant is safe and effective for those who cannot get a human kidney.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
50 people
Ages
40 years to 70 years
Study type
Interventional

Who can take part

  • You must be on dialysis for at least 6 months and have a working access (fistula, graft, or catheter).
  • You must be between 50 and 70 years old, or 40 to 49 with very high antibody levels (cPRA ≥99.9%).
  • You must live within 3 hours of the transplant center.
  • You need to be up to date on certain vaccines and have had past infections with CMV and Epstein-Barr virus (common viruses).
  • You cannot have other serious medical issues like advanced heart or lung disease, active cancer, or uncontrolled diabetes.
  • You must be willing and able to follow all study requirements and not have a history of medical noncompliance.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06878560Recruiting· Phase 1/Phase 2
Pig kidney transplant for kidney failure patients

This trial tests a special pig kidney (10 GE Xenokidney) as a transplant option for people with kidney failure who cannot get a human kidney. It aims to offer a life-saving alternative.

Chicago, Illinois
NCT06777719Recruiting· Phase 1
A study of immune cells to prevent kidney rejection

This trial tests if giving you back specially grown immune cells (called Tregs) made from your own blood can help your body accept a new kidney from a living donor with less rejection. It is for people who are ready for a first kidney transplant.

Nantes
NCT07696962Not yet recruiting· Phase 1
Pig kidney transplant for kidney failure

This study tests a new type of kidney transplant — using a kidney from a specially bred pig — for people with end-stage kidney disease who are on dialysis and have a low chance of getting a human kidney. The goal is to see if this pig kidney can work safely and help them live without dialysis.

New York, New York
NCT04571203Recruiting· Phase 1
Kidney transplant plus blood-cell treatment to help the graft settle

This Phase 1 study tests a treatment plan (including rabbit medicine and a low dose of radiation) meant to help the new kidney “take” and work longer. It also includes a kidney-from-deceased-donor process and checks how safely the treatment works in people with end-stage kidney disease.

Palo Alto, California
NCT05508009Recruiting· Phase 1/Phase 2
Kidney transplant with donor-matched stem cell treatment

This early-phase trial tests a stem cell transplant from a donor who is an extremely close match, given to people who are about to receive a kidney transplant from the same donor. The goal is to improve how well the new kidney works by resetting the immune system to better accept the transplant.

Palo Alto, California
NCT06809075Recruiting
Stem cell therapy to help highly sensitized patients get a kidney transplant

This trial tests if a special stem cell treatment (using your own stem cells) can reset your immune system so you can accept a kidney from a deceased donor, even if you have very high antibody levels that make it hard to find a match. It's for people who have been waiting a long time and haven't had a transplant offer.

Barcelona

Hear when a new Kidney Transplantation trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.