New treatment for bile duct cancer with heat, immunotherapy, and chemo
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of heat therapy inside the bile duct (endobiliary RFA) with immunotherapy (durvalumab) and chemotherapy (gemcitabine and cisplatin) for people with unresectable extrahepatic cholangiocarcinoma. The goal is to see if adding the heat treatment improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with bile duct cancer outside the liver that cannot be removed by surgery.
- You have a blocked bile duct that needs to be drained or you already have a drain in place.
- You are about to start your first treatment with the drugs durvalumab, gemcitabine, and cisplatin.
- You are at least 18 years old.
- You have not had radiation or chemotherapy for this cancer before.
- You do not have a permanent metal stent in your bile duct that cannot be removed with a scope.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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