Stapokibart for non-allergic rhinitis with high eosinophils
Treatments studied
Part of Ear, nose & throat, Immune system & allergy clinical trials.
This study tests a new medication (stapokibart) for people with a specific type of non-allergic rhinitis where eosinophils (a type of white blood cell) are high in the nose. The trial aims to see if the drug can reduce nasal symptoms like stuffiness, runny nose, and sneezing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must have had nasal symptoms (like stuffy nose, runny nose, sneezing, or itching) for at least 2 years.
- You must have tested negative for allergies (blood test or skin prick test).
- Your nasal mucus must have high levels of eosinophils (a type of white blood cell) — above 20%.
- Your symptoms must not be well controlled with standard nasal sprays or other allergy medicines.
- You must be willing to use reliable birth control during the study and for 3 months after the last dose.
- You must not have certain other medical conditions, like severe asthma, chronic sinusitis, or recent nasal surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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