Comparing two IV fluids for initial sepsis treatment
Part of Infections clinical trials.
This trial compares two common IV fluids (normal saline and Ringer's lactate) to see which one works better for initial hydration in people with sepsis in the emergency department. It aims to find the safest and most effective way to give fluids early in sepsis treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have a confirmed or suspected infection that caused sepsis.
- You are not receiving CPR or on a breathing tube (intubated) right now.
- You are not pregnant.
- You do not have other serious conditions like heart failure, severe kidney failure, high calcium, or liver disease that might make the fluids unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a simple blood test to measure how your blood vessels leak fluid during septic shock. The results may help doctors give the right amount of fluids to keep you stable.
This trial tests a personalized approach to giving IV fluids to patients with sepsis in the emergency department. It uses a device to monitor your heart and blood flow to help doctors decide how much fluid you need, which may improve recovery.
This study tests a personalized approach to giving fluids to patients with sepsis, a serious infection that can cause low blood pressure. The goal is to see if individualized fluid resuscitation improves outcomes compared to standard care.
This trial tests a new treatment to protect and repair the layer of cells lining your blood vessels (glycocalyx) during sepsis. It aims to improve recovery from severe infections.
This trial tests whether a fluid called Gelaspan (a gelatin-based IV fluid) is better for treating sepsis patients who need emergency abdominal surgery than standard crystalloid fluids. It checks if you have a belly infection and high lactate levels, and you must not have serious heart, lung, or kidney problems.
This Phase 3 trial tests whether starting a medicine called norepinephrine early can improve outcomes for adults with sepsis (a serious body-wide response to infection) and low blood pressure. You might be considered if you’re very early in hospital care and meet specific blood pressure and lactate tests.
Hear when a new Sepsis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.