Testing a new heart valve device for leaky valves
Part of Heart & circulation clinical trials.
This study tests the Cephea valve, a less invasive option for people with severe mitral valve leakage or narrowing who are not good candidates for open-heart surgery. It checks if the device can safely improve valve function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe mitral valve disease causing significant backward flow (leak) or narrowing.
- Your left ventricle pumps at least 30% of its blood out each beat (LVEF ≥ 30%).
- Your heart team has decided that a procedure through a catheter (tube) is better for you than open-heart surgery.
- You have not had any prior heart valve treatment that would block or affect this new valve.
- You do not need emergency or very urgent heart surgery right now.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new mitral valve device that may improve blood flow in people with significant mitral valve leakage or narrowing, using a catheter instead of open-heart surgery. It’s meant for patients who doctors think this catheter approach is a better fit than surgery.
This study tracks people with mitral valve disease who receive the Cephea valve through a tube in an artery rather than open-heart surgery. It looks at how well the valve works over time.
This study looks at how long a new mitral valve treatment/device can stay working in people with moderate-to-severe or severe mitral valve leak. It may help avoid or delay surgery for people considered higher risk for mitral valve repair.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
This study looks at how safe and effective a specific catheter procedure is for people with moderate-to-severe mitral valve leakage. It may help those who are considered high risk for traditional open-heart surgery.
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