Testing Higher Doses of Rectal Indomethacin to Prevent Pancreatitis after ERCP
Part of Digestive system clinical trials.
This trial is testing whether higher doses of a common anti-inflammatory drug (indomethacin) given as a suppository can better prevent pancreatitis after an ERCP procedure in people who are at high risk for this complication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your doctor has determined you are at high risk for pancreatitis after an ERCP procedure
- You are willing to sign a consent form
- You do not have current pancreatitis or a tumor on the ampulla (the opening where bile enters the intestine)
- You can safely take nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen (no allergies, kidney problems, or active stomach ulcers)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares a low dose of indomethacin (a pain reliever) with the standard dose to see if it works just as well for preventing pancreatitis (inflammation of the pancreas) after an ERCP procedure. It may reduce side effects while still protecting your pancreas.
This study compares indomethacin (an anti-inflammatory medicine) against using a temporary pancreatic stent to prevent pancreatitis after an ERCP procedure. It may help you lower the chance of painful inflammation of the pancreas after ERCP.
This study tests whether a rectal suppository of indomethacin (a type of anti-inflammatory) can help prevent complications during a bile duct procedure called ERCP. It's for people who have already had a prior bile duct cut.
This trial tests whether giving extra IV fluids before, during, and after an ERCP procedure can help prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). If you are scheduled for an ERCP, you may be eligible to participate.
This trial tests whether a single dose of tacrolimus, a medicine that calms the immune system, can lower the chance of developing pancreatitis (inflammation of the pancreas) after an ERCP procedure. ERCP is a procedure used to diagnose or treat problems in the bile ducts or pancreas.
This trial tests whether parecoxib or indomethacin works better at preventing pancreatitis, a common complication after a procedure called ERCP. Participants will receive one of the two medicines before the procedure, and the study will track which one is safer and more effective.
Hear when a new Post-ERCP Pancreatitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.