Higher doses of rectal indomethacin to prevent post-ERCP pancreatitis
Part of Digestive system clinical trials.
This study tests giving indomethacin (a type of anti-inflammatory medicine) through the rectum in different doses to people having an ERCP (a procedure to look at bile and pancreas tubes), aiming to prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). You may join if you are at high risk for this complication and meet the other health requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- Your doctor must consider you at high risk for pancreatitis after an ERCP procedure.
- You must be able to give written consent to participate.
- You must not have certain pancreatic or digestive conditions (like a blocked papilla, altered stomach anatomy, or an active acute pancreatitis episode).
- You must not have a pancreatic stent in place during the procedure.
- You must not have allergies to NSAIDs (like ibuprofen), kidney problems, or an active stomach ulcer.
- You must not be pregnant or breastfeeding, and you must not have severe heart or lung disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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