Tacrolimus to prevent inflammation after ERCP
Treatments studied
This trial tests whether a single dose of tacrolimus, a medicine that calms the immune system, can lower the chance of developing pancreatitis (inflammation of the pancreas) after an ERCP procedure. ERCP is a procedure used to diagnose or treat problems in the bile ducts or pancreas.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your doctor has recommended an ERCP procedure for you.
- You have not had a previous sphincterotomy or sphincteroplasty (procedures that cut or widen the muscle around the bile duct opening).
- You do not have chronic pancreatitis (long-term inflammation of the pancreas) or active pancreatitis (current sudden inflammation).
- You do not have severe kidney problems (eGFR below 30 mL/min).
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing whether higher doses of a common anti-inflammatory drug (indomethacin) given as a suppository can better prevent pancreatitis after an ERCP procedure in people who are at high risk for this complication.
This study compares indomethacin (an anti-inflammatory medicine) against using a temporary pancreatic stent to prevent pancreatitis after an ERCP procedure. It may help you lower the chance of painful inflammation of the pancreas after ERCP.
This trial tests whether giving extra IV fluids before, during, and after an ERCP procedure can help prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). If you are scheduled for an ERCP, you may be eligible to participate.
This Phase 3 study tests whether putting an anti-inflammatory medicine into the rectum (indomethacin) plus taking an immune-suppressing pill (tacrolimus) works better than using the two medicines in a different combination to prevent pancreatitis after an ERCP procedure. If you qualify, you may be assigned to one of the treatment options to lower your risk of post-ERCP pancreas inflammation.
This trial tests whether taking diclofenac (an anti-inflammatory medicine) can lower the chance of getting pancreatitis after a procedure called ERCP. If you qualify, you may help researchers find a safer way to prevent this complication.
This study tests whether giving lidocaine during an ERCP procedure can lower the risk of a painful complication called pancreatitis. If you’re scheduled for ERCP with a “never-treated” opening, this trial may see if lidocaine helps you avoid post-procedure pancreas inflammation.
Hear when a new Post-ERCP Pancreatitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.