Tacrolimus to prevent pancreatitis after ERCP
Treatments studied
Part of Digestive system clinical trials.
This trial tests whether a drug called tacrolimus can reduce the risk of pancreatitis (inflammation of the pancreas) after a procedure called ERCP, which is used to diagnose and treat problems in the bile ducts or pancreas. If you are scheduled for an ERCP, this study may help prevent a common complication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for an ERCP procedure.
- You have not had a previous sphincterotomy or sphincteroplasty (procedures that cut the muscle around the bile duct).
- You do not have chronic pancreatitis or active pancreatitis.
- You are not currently taking tacrolimus, ciclosporin, or certain other medications that interact with tacrolimus.
- You are not pregnant or breastfeeding, and you do not have severe kidney problems or high potassium levels.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares indomethacin (an anti-inflammatory medicine) against using a temporary pancreatic stent to prevent pancreatitis after an ERCP procedure. It may help you lower the chance of painful inflammation of the pancreas after ERCP.
This trial tests whether giving extra IV fluids before, during, and after an ERCP procedure can help prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). If you are scheduled for an ERCP, you may be eligible to participate.
This study tests giving indomethacin (a type of anti-inflammatory medicine) through the rectum in different doses to people having an ERCP (a procedure to look at bile and pancreas tubes), aiming to prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). You may join if you are at high risk for this complication and meet the other health requirements.
This study tests whether a rectal dose of indomethacin (an anti-inflammatory drug) can help prevent complications after an ERCP. It is for people who have already had a sphincterotomy and are having another ERCP to treat bile duct issues.
This Phase 3 study tests whether putting an anti-inflammatory medicine into the rectum (indomethacin) plus taking an immune-suppressing pill (tacrolimus) works better than using the two medicines in a different combination to prevent pancreatitis after an ERCP procedure. If you qualify, you may be assigned to one of the treatment options to lower your risk of post-ERCP pancreas inflammation.
This trial tests whether giving an anti-inflammatory drug (diclofenac) before an ERCP procedure can help prevent a common complication called pancreatitis (inflammation of the pancreas). If you are scheduled for ERCP, you may be able to participate.
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