Treating stubborn facial pain

This trial tests whether giving a numbing medicine (lidocaine) into a small artery in the face (the external carotid artery) can help people with hard-to-treat chronic migraines or persistent face/skull pain. It is for those who haven't found relief from standard treatments.

This trial tests a new cognitive-behavioral therapy (a type of talk therapy) for people with chronic orofacial pain – pain in the face, mouth, or jaw that has lasted for months. The goal is to learn skills to help manage pain and improve quality of life.

This trial tests if a non-invasive brain stimulation technique (called TMS or tDCS) can help reduce long-lasting pain in the face, jaw, or mouth. It's for people who have tried other treatments without enough relief.

This study compares two pain-relieving medicines given through an IV to see which works better for people with difficult-to-treat face or mouth pain. It may help you if other treatments have not worked.

This study uses brain scans (MRI) to better understand persistent pain in the face or mouth (PIFP) compared to people without pain. If you join, you'll have an MRI and possibly some mild stimulation to help researchers learn more about the condition.

This study tests a device implanted in the brain that may reduce long-lasting nerve pain that has not improved with other treatments. It could help people with pain after nerve injury, stroke, or other conditions.