Clinical trials
Facial Pain clinical trials
Below are recruiting facial pain clinical trials, each written for real people, not researchers. We’re tracking 14 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07250984Enrolling by invitation
Treating stubborn facial pain
This trial tests a treatment for unusual facial pain that doesn't get better with standard care. It may help if you have facial pain and no psychiatric condition.
LjubljanaAges 18–75 - NCT07123233Recruiting
Cognitive behavioral treatment for chronic face and mouth pain
This trial tests a new cognitive-behavioral therapy (a type of talk therapy) for people with chronic orofacial pain – pain in the face, mouth, or jaw that has lasted for months. The goal is to learn skills to help manage pain and improve quality of life.
MilanAges 18–70 - NCT07187388Recruiting
Electrical stimulation for jaw pain in motor neuron disease
This study tests whether gentle electrical stimulation around the jaw can ease facial pain, improve jaw movement, and help oral health in people with certain motor neuron diseases like ALS or PLS. It may be a good fit if you have jaw pain and meet a few health conditions.
Davie, FloridaAges 18 years+ - NCT06485856Recruiting
Pain tracking using facial movements for non-verbal patients
This trial tests a system that measures facial movements to assess pain in patients who cannot speak or communicate verbally, such as those with a breathing tube. It may help healthcare providers better understand and manage pain in these patients.
AdanaAges 18 years+ - NCT06518421Recruiting
Emotions and Memory in Chronic Facial Nerve Pain
This study looks at how emotions and memory are affected in people with chronic trigeminal neuralgia (a type of facial nerve pain). Participants will have an MRI scan and fill out questionnaires to help researchers understand the link between chronic pain and cognitive changes.
Toronto, OntarioAges 35–60 - NCT05961501Enrolling by invitationPhase 2/Phase 3
CBD and CBN for long-lasting facial pain and muscle headaches
This trial tests whether CBD and CBN can reduce facial pain and headaches caused by muscle-related problems that have lasted more than 3 months. It may help people who have ongoing symptoms find a new treatment option.
WroclawAges 18 years+ - NCT07262632Recruiting
Cancer pain and AI assessment study
This study builds a database of videos and voice recordings from people with cancer, both with and without pain. The goal is to train artificial intelligence (AI) to automatically recognize pain, which could help doctors better manage it in the future.
Rotterdam, South HollandAges 18 years+ - NCT07754266Recruiting
Headache, ear, and dizziness registry
This study collects information from people who have headaches, ear problems, dizziness, or sinus issues to better understand these symptoms and how they relate to migraine. Your participation may help improve future treatments and diagnosis.
North Kingstown, Rhode IslandAges 18 years+ - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT07611643Recruiting
Treating Jaw Clenching and Facial Pain With a Custom Bite Guard
This study tests whether a custom-made bite guard (called an occlusal splint) can help relieve jaw and facial pain caused by temporomandibular disorders—conditions affecting the jaw joint and muscles. Researchers will monitor how well the treatment works and how it affects your symptoms.
Roma, RomaAges 18 years+ - NCT06429501RecruitingPhase 2
Numbing medicine for facial fracture surgery
This study tests numbing medicine (local anesthetic) given during surgery for broken facial bones, like the jaw or cheekbones. The goal is to see how well it works and if it helps recovery.
St Louis, MissouriAges 18 years+ - NCT06813352Recruiting
Using facial expressions to recognize pain in fibromyalgia
This study uses artificial intelligence to look at facial expressions and other body signals to help recognize pain in people with fibromyalgia. It may lead to better ways to measure and treat pain.
Belo Horizonte, Minas GeraisAges 18–65 - NCT07745972Recruiting
Pain relief block for gallbladder surgery
This trial tests a numbing injection near the ribs to reduce pain after laparoscopic gallbladder removal. It may help you recover with less discomfort.
IstanbulAges 18–80 - NCT07006610Recruiting
Tape or cooling therapy for jaw surgery recovery
This study tests whether cooling with a hilotherapy device or taping with kinesio tape helps reduce swelling and pain after double-jaw surgery. Results may lead to a gentler recovery for you.
Istanbul, BağcılarAges 18–50
Hear when a new Facial Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for facial pain?
- Yes. Clin2 currently lists 14 recruiting facial pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a facial pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a facial pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.