Testosterone and estrogen cream vs. estrogen alone for vulvodynia
Part of Kidney & urinary, Mental health, Women’s health & pregnancy clinical trials.
This trial compares two creams for vulvodynia pain. One contains both testosterone and estrogen, the other only estrogen. The study aims to see if the combination works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with vulvodynia and have pain during vaginal penetration that you rate as 4 or higher on a pain scale.
- You do not have an active vaginal infection.
- You are not pregnant or breastfeeding.
- You are not taking finasteride or dutasteride (medications for hair loss or prostate issues).
- You are not using any other hormone creams or ointments on your vulva or vagina.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a topical cream called ketotifen for treating a type of vulvar pain (secondary provoked vestibulodynia). The cream may help reduce pain at the vaginal opening, and you would apply it daily for several months.
This study compares two different surgery techniques for people with long-lasting, touch-triggered pain at the vaginal entrance (“vestibule”). You might be offered one of the surgical approaches and you’ll complete pain testing and follow-up measurements to see which technique works best.
This trial studies a treatment for long-lasting vaginal/vulvar irritation caused by conditions like vaginal atrophy or certain skin conditions of the vulva. You would try the study product/device and be followed over time to see how symptoms recover.
This trial compares a vibrating vaginal device to standard therapy for women with pain during sex. It aims to find a more effective and comfortable treatment option.
This study compares two vaginal treatments—DHEA and estradiol—to help relieve common menopause symptoms like dryness, itching, or discomfort during sex. You'll use vaginal therapy (applied directly where symptoms occur) and help researchers understand which works better.
This trial compares three treatments for vulvar lichen sclerosus: a steroid ointment, a non-steroid ointment, and platelet-rich plasma therapy. It aims to see which works best for managing symptoms and improving skin health.
Hear when a new Vulvodynia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.