Low-dose naltrexone for vulvar pain
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This study tests a low dose of naltrexone (a pill that may help reduce pain) for vulvodynia, a condition causing long-lasting pain in the vulvar area. It aims to see if this treatment can ease the pain and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 3 months after giving birth.
- You have had vulvar pain for at least 3 months that is not explained by another condition.
- You are not pregnant or breastfeeding and are willing to use contraception if you could become pregnant.
- You have not used other vulvodynia treatments (except hormonal therapy) in the last 3 months, and no botox injections in the vulvar area in the last year.
- You have not used opioids (like painkillers, cough medicine, or anti-diarrhea meds) in the last 2 weeks, and your urine test shows no opioids.
- You do not have liver or kidney problems, or a history of suicidal thoughts or attempts.
- You are willing to avoid driving or heavy machinery until you know how the drug affects you.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 2 study tests whether low-dose naltrexone can reduce pain from vulvodynia. It also looks at how well it works across different vulvodynia types, comparing to what participants are already doing for symptoms.
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