Zanubrutinib plus rituximab for HLH with B-cell lymphoma
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This study tests a combination of two drugs—zanubrutinib and rituximab—to treat HLH that happens in people with B-cell lymphoma. It aims to see if this treatment is safe and works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have HLH with B-cell lymphoma (or strong suspicion of it) or an increase in CD20-positive B cells in your bone marrow.
- You should be between 14 and 80 years old.
- Your heart, kidneys, and liver should be in good enough shape (no severe failure).
- You must not have a serious active infection or be pregnant.
- You need to agree to use effective birth control during and after the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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