Propranolol for misophonia: a pilot study
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests if a blood pressure medication called propranolol can reduce the intense anger or anxiety some people feel in response to everyday sounds (like chewing or breathing). If you have misophonia and meet the study’s health and safety criteria, you may be able to join and receive the medication under medical supervision at a clinic in Littleton, Colorado.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with misophonia that causes significant distress (moderate or higher on a standard scale).
- You can travel to the study site in Littleton, Colorado for visits.
- You are not currently taking propranolol or another beta-blocker, and you don’t have certain heart or lung conditions (like asthma or low blood pressure).
- You are not pregnant or nursing, and you can follow the study clinic’s safety rules.
- You have not had recent mental health emergencies (like suicidal thoughts or psychosis) or misophonia-related dangerous behaviors in the past year.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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