Comparing surgery order for liver spread from colon cancer

This study looks at whether a liver transplant can help people whose colorectal cancer has spread to the liver but cannot be removed by surgery. It also checks whether certain cancer features, treatment history, and blood/health status make transplant safer or more effective.

This study compares three different surgical approaches for patients whose colorectal cancer has spread to the liver. Researchers want to understand which surgical order works best, how it affects quality of life, and the costs involved.

This trial compares having one surgery to remove both the colon tumor and liver tumors at the same time versus having two separate surgeries. It aims to find which approach is safer and works better for patients whose cancer has spread only to the liver.

This trial compares two surgical approaches for removing liver metastases from colon cancer: anatomical resection versus nonanatomical resection. It aims to see which approach works better for people whose tumors have certain genetic changes or are on the right side of the colon.

This trial tests a two-step surgery for colorectal cancer that has spread only to the liver. The goal is to remove all visible liver tumors by first dividing the liver and blocking blood flow to the diseased side, which helps the healthy side grow larger so it can be safely removed in a second surgery.

This trial compares liver transplant versus liver surgery for people whose colorectal cancer has spread only to the liver and cannot be removed initially. You would first receive chemotherapy to shrink the tumors, and if they become removable, you may be randomly assigned to have a liver transplant or standard liver surgery.