Transplant vs surgery after chemo for liver-only colorectal cancer
Part of Cancer, Digestive system clinical trials.
This trial compares liver transplant versus liver surgery for people whose colorectal cancer has spread only to the liver and cannot be removed initially. You would first receive chemotherapy to shrink the tumors, and if they become removable, you may be randomly assigned to have a liver transplant or standard liver surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have colorectal cancer that has spread only to the liver and is not removable at first.
- You are 18 or older and in fairly good health (able to do daily activities).
- Your cancer has a normal DNA repair system (MSS) and certain gene mutations (BRAF V600E) must have responded to treatment.
- You have not had previous chemotherapy for the spread of cancer.
- After chemo, your cancer shrinks or stays stable for at least 3 months and your CEA tumor marker drops by half or is below 80 ng/mL.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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