Preventing hearing loss from cisplatin in head and neck cancer
Part of Ear, nose & throat clinical trials.
This trial tests whether a gel placed in the ear can protect against hearing loss caused by high-dose cisplatin chemotherapy. It is for people with head and neck cancer who are scheduled to receive a certain amount of cisplatin.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have head or neck cancer that can be treated with high-dose cisplatin (at least 200 mg/m² total).
- You are able to give written consent and are 18 or older.
- Your hearing before treatment is similar in both ears and not worse than a mild loss.
- You are not getting more than 30 Gy of radiation to the inner ear area.
- You do not have any ear problems that would prevent the gel from reaching the round window.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at how cisplatin chemotherapy affects hearing and balance in people with head and neck cancer. It compares those getting cisplatin-based treatment to those getting only radiation. The goal is to better understand and potentially reduce these side effects.
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