Prevent hearing damage during cisplatin chemotherapy
Part of Brain & nervous system, Ear, nose & throat clinical trials.
This Phase 2 trial tests whether sodium thiosulfate and mannitol can reduce hearing damage (ototoxicity) in adults receiving cisplatin chemotherapy. It may help protect hearing while you get cancer treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and starting cisplatin chemotherapy as part of your cancer care
- You can sign consent and follow the study plan
- Your general function is good (ECOG 0 to 2, meaning you are able to do most daily activities)
- If you can become pregnant: you must have a negative pregnancy test and agree to reliable birth control during the study
- Your kidney function is not significantly reduced (creatinine clearance 60 mL/min or higher)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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