Clin2
NCT07284693Likely a fitNot yet recruiting

Phenolic complex therapy for attention in children with Down syndrome

Cognitive Functions

Part of Brain & nervous system, Genetic & congenital clinical trials.

This trial tests a natural phenolic complex (K110-42) to see if it can improve attention and focus in children with Down syndrome. It may help if your child struggles with concentration and is between 4 and 8 years old.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
108 people
Ages
4 years to 8 years
Study type
Interventional

Who can take part

  • Your child must have a genetic diagnosis of Down syndrome (Trisomy 21).
  • Your child must be between 4 and 8 years old.
  • Your child has trouble with attention or focus, as reported by you or a doctor.
  • Your child cannot have other serious neurological conditions like autism or epilepsy.
  • Your child cannot be on ADHD medications or cognitive-enhancing supplements.
  • Your child must have an IQ of 55% or higher.
  • Your child cannot have hypothyroidism or certain chronic health issues like liver, kidney, or autoimmune disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07531940Not yet recruiting· Phase 1
Testing Memantine Doses in Down Syndrome

This study tests whether a medicine called memantine (already used for memory problems) can help people with Down syndrome think and remember better. Researchers will try different doses to find what works best and is safest.

Cleveland, Ohio
NCT06465823Recruiting· Phase 2
Bumetanide for thinking skills in Down syndrome

This trial tests whether a medication called bumetanide can improve thinking and learning skills in teenagers with Down syndrome. It is a 10-week study that compares bumetanide to a placebo (a pill with no medicine).

Rome
NCT05301361Enrolling by invitation· Phase 1
Test of brain testing during stimulant treatment for ADHD

This trial checks whether a “NIH Toolbox” set of child-friendly tests can detect changes when stimulant medicine is used for ADHD. It may help doctors better measure how well stimulant treatment is working in people with intellectual disability.

Sacramento, California
NCT07278492Not yet recruiting· Phase 1
NAD boost to prevent Alzheimer's in Down syndrome

This study tests whether a supplement that boosts a natural substance called NAD (which helps cells work properly) can slow or stop memory loss in people with Down syndrome. You and your caregiver would visit a clinic for regular checkups and take the supplement daily.

Boston, Massachusetts
NCT07086313Recruiting· Phase 2/Phase 3
Testing a new ADHD drug for children

This trial tests an experimental drug (EB-1020) for children with ADHD. It aims to see if the drug is safe and effective in reducing ADHD symptoms.

Sapporo
NCT07334912Recruiting· Phase 2
Study of AEF0217 for people with Down syndrome

This study tests if an investigational drug called AEF0217 can help improve thinking and daily living skills in people with Down syndrome. It's for ages 16-32 who have a caregiver to support them throughout the trial.

Bordeaux

Hear when a new Cognitive Functions trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.