Hormone treatment to study thinking in Down syndrome
Treatments studied
Part of Brain & nervous system, Genetic & congenital, Mental health clinical trials.
This trial studies whether a GnRH hormone treatment can improve thinking and memory in people with Down syndrome. It also checks safety and whether the treatment affects brain-related changes seen on MRI.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of Down syndrome (trisomy 21)
- You can understand and follow the study steps (has verbal expression to participate)
- You agree to reliable, non-hormonal birth control for the whole study (for people who can get pregnant and their partners)
- You are not currently dealing with an acute illness that would require hospitalization
- You are not taking certain medicines that affect hormones (or related brain medicines), and you can be checked/confirmed
- You can safely do MRI scans (no metal/pacemaker and you agree to be informed only about allowed incidental findings)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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