Chinese herbal treatment for moyamoya disease: CHIMES trial
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether a Chinese herbal formula called Qiqi Shengmai can help people with moyamoya disease, a rare condition where blood vessels in the brain become narrow. It aims to see if the herbal treatment is safe and may improve symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have moyamoya disease diagnosed by brain imaging.
- You must be between 18 and 80 years old.
- You must be willing to take traditional Chinese medicine and have a specific pattern of liver-yang hyperactivity as determined by a Chinese medicine doctor.
- You must not have had a stroke or mini-stroke in the last 6 weeks.
- You must not be allergic to the herbal formula or contrast agents used in imaging.
- You must not be pregnant, breastfeeding, or planning brain bypass surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial follows people with moyamoya disease who are treated with medication only, and it also looks at first-degree relatives. The goal is to understand long-term outcomes and whether careful conservative care is beneficial over time.
This trial tests whether a daily aspirin regimen combined with a blood-pressure cuff treatment on the arm can slow the progression of mild moyamoya disease. It aims to reduce the risk of strokes and bleeding events.
This study tests if statins (cholesterol-lowering drugs) can help people with Moyamoya disease. The trial will follow patients who receive either surgery or standard care to see if adding a statin improves outcomes.
This trial tests whether exosomes made from special stem cells can help people with Moyamoya disease who still have symptoms after surgery. It aims to improve blood flow to the brain and reduce future strokes.
This study looks at why some people with moyamoya disease have trouble with thinking and memory. It may help find better ways to understand and treat these problems.
This study at Vanderbilt tests whether certain biomarkers (signs in your blood or brain scans) can help tailor care for people with Moyamoya, a condition where blood flow to the brain is reduced. Participants will have brain scans and complete study procedures before and after surgery to improve blood flow.
Hear when a new Moyamoya Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.