Exosomes for Moyamoya disease treatment trial
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether exosomes made from special stem cells can help people with Moyamoya disease who still have symptoms after surgery. It aims to improve blood flow to the brain and reduce future strokes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old and have Moyamoya disease confirmed by imaging tests like MRI or angiogram.
- You have already had a surgery called temporal muscle patch but did not get enough improvement.
- It has been at least 3 months since your surgery, and tests show poor blood flow or ongoing brain ischemia.
- You still have symptoms of Moyamoya disease, such as mini-strokes (TIAs) or stroke-like episodes.
- Your blood and organ function tests are within safe ranges for the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial follows people with moyamoya disease who are treated with medication only, and it also looks at first-degree relatives. The goal is to understand long-term outcomes and whether careful conservative care is beneficial over time.
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This study is building a tool to predict how people with moyamoya disease will do after brain surgery to improve blood flow. If you are an adult with moyamoya and are scheduled for this surgery, you may be able to help.
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
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