Clin2
NCT07288216Possibly a fitRecruiting

Switching to KPL-387 alone for well-controlled pericarditis

Recurrent PericarditisHeart DiseasesPericarditis

Part of Heart & circulation clinical trials.

This study tests whether a new drug, KPL-387, can keep your pericarditis under control as your only treatment, after you have been stable on other medicines. It is for people whose pericarditis is well controlled now but who have had flares in the past.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
120 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • Your pericarditis must be well controlled right now (pain score 3 or less out of 10 and low inflammation blood test).
  • You must have had at least one past pericarditis flare with high inflammation (CRP > 1 mg/dL).
  • You have been on a stable dose of standard pericarditis medicines (like NSAIDs, colchicine, steroids, or certain biologics) for at least 3 months.
  • You cannot have had a pericarditis flare in the last 3 months.
  • You cannot have active or untreated tuberculosis, a weak immune system, HIV, recent serious infections, certain cancers, or an organ transplant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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