Clin2
NCT07289178Possibly a fitNot yet recruiting

Numbing injection to prevent long-term pain after mastectomy

Serratus Plane BlockPostoperative HyperalgesiaChronic Post-surgical PainLiposomal BupivacaineRadical Mastectomy Surgery

Part of Pain clinical trials.

This study tests whether a numbing injection (liposome bupivacaine) into the chest wall muscles before surgery can reduce long-term pain and sensitivity after mastectomy. It may help prevent chronic pain following breast cancer surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
120 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are scheduled for a radical mastectomy (complete removal of the breast) for breast cancer.
  • You are between 18 and 80 years old.
  • You do not have chronic pain or take strong painkillers (like morphine) regularly.
  • You have no history of chest surgery or serious chest injury.
  • You are not allergic to numbing medicines like lidocaine or bupivacaine.
  • Your body mass index (BMI) is 30 or lower.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07661212Not yet recruiting
Timing of a nerve block for mastectomy surgery

This trial tests whether giving a nerve block (a numbing injection near the chest muscles) before or after mastectomy surgery affects pain and recovery. It may help you have less pain and a smoother recovery after your mastectomy.

Istanbul
NCT06502067Not yet recruiting
Numbing injection for less pain after breast surgery

This trial tests whether a special numbing injection (called a serratus posterior intercostal plane block) can reduce pain and inflammation after breast surgery. It may help you recover with less pain and fewer side effects.

NCT07670078Not yet recruiting
Comparing pain block amounts for breast cancer surgery

This trial tests whether using different amounts of a pain-blocking injection (serratus posterior superior intercostal plane block) can reduce pain after breast cancer surgery. It aims to find the best dose for comfort and recovery.

Sivas, Sivas
NCT07579650Recruiting
Nerve Block for Pain Relief After Breast Surgery

This trial tests a special numbing technique (called a serratus posterior superior intercostal plane block) to help reduce pain after mastectomy surgery. The goal is to see if this nerve block reduces the need for pain medications after your procedure.

Diyarbakır, Outside of the US
NCT07510269Recruiting
Nerve blocks for pain control during mastectomy

This study tests two different numbing shots for the chest wall to see which one provides better pain relief during and after mastectomy surgery.

Bursa, Nilüfer
NCT07737132Not yet recruiting
Comparing two pain-block methods for mastectomy recovery

This study tests two different nerve blocks to see which one provides better pain relief after a mastectomy. If you are having a modified radical mastectomy, you may qualify to help researchers find the most effective way to manage pain after surgery.

Hear when a new Chronic Post-surgical Pain trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.