Lung valve treatment for tuberculosis cavities
Part of Infections, Lungs & breathing clinical trials.
This study tests a small valve placed in your airway to close off lung cavities caused by tuberculosis or a related infection. It may help stop bleeding, reduce infection, and improve your condition when surgery is not possible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have lung cavities (holes) caused by TB or NTM infection that are not suitable for surgery because of extensive lung damage.
- You meet at least one of these: your infection is hard to treat or resistant to drugs, you have another serious health condition (like diabetes or HIV) that makes drug treatment risky, or you have repeated coughing up of blood.
- You must be able to have a bronchoscopy (a tube test on your lungs).
- You are not pregnant, have no severe heart or mental health issues, no asthma, and are not allergic to nickel, titanium, or silicone.
- You have quit smoking and do not have an active lung infection or large bullae (air pockets) covering more than 30% of a lung.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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