Combination therapy for severe ulcerative colitis
Treatments studied
Part of Digestive system clinical trials.
This trial tests if combining two medications, infliximab and tofacitinib, works better than standard treatment for adults hospitalized with a severe flare of ulcerative colitis. If you have not been on these drugs before and meet certain health criteria, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are hospitalized for a severe flare of ulcerative colitis.
- You have not taken infliximab or tofacitinib before.
- You do not have active tuberculosis or a history of blood clots.
- You are not pregnant or breastfeeding.
- You have no other serious bowel conditions like Crohn's disease or a megacolon.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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