Clin2
NCT07299825Possibly a fitRecruiting

Study of A166 for advanced HER2-positive breast cancer

Her 2 Positive Breast Cancer

Part of Cancer clinical trials.

This trial tests a new drug called A166 for people with HER2-positive breast cancer that has spread or can't be removed. It is for those who have already tried up to five treatments, including a specific type of HER2 antibody-drug conjugate.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are 18 to 75 years old.
  • You have been diagnosed with breast cancer that is advanced or has spread to other parts of the body.
  • You have had no more than 5 different treatments for advanced disease, and at least one included a HER2 antibody-drug conjugate with a topoisomerase inhibitor.
  • Your cancer has worsened or you could not tolerate your most recent treatment.
  • You have at least one tumor that can be measured on scans.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07664150Recruiting· Phase 1/Phase 2
Testing a new drug for HER2-positive cancers after other treatments stop working

This trial tests a new drug, CAN016, for people with advanced solid tumors that have HER2 expression or a HER2 gene change. You may qualify if your cancer has gotten worse after trying other HER2-targeted treatments.

Beijing, Beijing Municipality
NCT06433609Recruiting· Phase 2
ADC plus immunotherapy for advanced HER2-negative breast cancer

This trial tests a combination of an antibody-drug conjugate (ADC) and an immunotherapy drug (adebrelimab) for people with advanced HER2-negative breast cancer that has stopped responding to prior treatments. The goal is to see if this combination can help shrink or slow the cancer.

Beijing, Beijing Municipality
NCT07560475Not yet recruiting· Phase 2
Different ways to give a new drug for HER2-positive breast cancer

This study tests a new drug called SHR-A1811, given by different methods, to find the best way to treat advanced HER2-positive breast cancer. It may help if you have had few treatments so far and have not had this type of drug before.

Tianjin
NCT07646626Recruiting· Phase 2
New antibody drugs for advanced HER2-positive cancers

This trial tests two new antibody drugs (SSGJ-705 and SSGJ-612), alone or combined with chemotherapy, in patients with advanced cancers that have a protein called HER2. The study aims to see if this combination can shrink tumors and help patients live longer.

Hangzhou, Zhejiang
NCT07527806Not yet recruiting· Phase 2
Personalized pre-surgery treatment for HER2-positive breast cancer

This trial tests different combinations of targeted therapy and chemotherapy before surgery for HER2-positive breast cancer. It uses a special PET scan to see how well the treatment is working and to help choose the best treatment plan for each person.

NCT07591090Recruiting· Phase 2
Drug combination study for advanced HER2-negative breast cancer

This study tests whether combining two new drugs (AK146D1 and AK112) can help people with advanced breast cancer that is HER2-negative (a type that doesn't have too much of a specific growth protein). The goal is to see if this combination can shrink tumors and improve survival.

Shanghai, Shanghai Municipality

Hear when a new HER-2 Positive Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.