Clin2
NCT07301229Possibly a fitNot yet recruiting

Study of HLX43 for advanced pancreatic cancer

Pancreatic Ductal Adenocarcinoma (PDAC)

Treatments studied

Part of Cancer, Digestive system clinical trials.

This study tests an experimental drug called HLX43 in people with advanced pancreatic cancer that has not responded to at least one previous treatment. The drug may help shrink tumors or slow the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with pancreatic ductal adenocarcinoma that is locally advanced or has spread, and it has not responded to at least one standard treatment.
  • You have at least one tumor that can be measured on a scan.
  • You are willing to provide a tumor tissue sample (either from a previous biopsy or a new one) for testing.
  • You have recovered from side effects of previous treatments (except for hair loss or mild nerve damage).
  • You are able to care for yourself (ECOG score 0-2) and are expected to live at least 3 more months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07115485Recruiting· Phase 2
Study of HLX43 for advanced stomach or junction cancer

This trial tests a new drug called HLX43 (an antibody-drug conjugate targeting PD-L1) for people with advanced stomach or gastroesophageal junction cancer that has progressed after at least one prior treatment. It aims to see if it can shrink tumors and help patients live longer.

Beijing
NCT07106892Recruiting· Phase 2
Testing HLX43 for advanced colorectal cancer

This trial tests a new drug, HLX43, that targets a protein called PD-L1 on cancer cells and delivers a chemotherapy-like payload directly to them. It's for people with advanced colorectal cancer that hasn't responded to standard treatments.

Beijing
NCT06907615Recruiting· Phase 2
Study of HLX43 for advanced non-small cell lung cancer

This trial tests a new drug, HLX43, for people with advanced non-small cell lung cancer that has not responded to standard treatments. It aims to see if HLX43 can help shrink or control the cancer.

Houston, Texas
NCT06742892Recruiting· Phase 2
Study of HLX43 for advanced liver cancer after standard treatment fails

This trial tests a new drug, HLX43, for people with advanced liver cancer (HCC) that has worsened or caused intolerable side effects after standard treatments like immunotherapy or targeted therapy. The goal is to see if HLX43 can help when other options have stopped working.

Hunan, Hunan
NCT06115642Enrolling by invitation· Phase 1
Study of HLX43 for advanced solid tumors

This trial tests a new drug called HLX43 for people with advanced or metastatic solid tumors that have not responded to standard treatments. It aims to find safe dosing and understand how the drug works in the body.

Stanford, California
NCT07253142Recruiting· Phase 2
Study of HLX43 with Serplulimab for advanced lung cancer

This trial tests a new combination of two drugs for people with advanced lung cancer that has worsened after previous treatments like chemotherapy or immunotherapy. The goal is to see if this approach can help shrink tumors or slow the disease.

Hefei, Anhui

Hear when a new Pancreatic Ductal Adenocarcinoma (PDAC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.