Guiding blood flow during Moyamoya surgery in children

This study is building a tool to predict how people with moyamoya disease will do after brain surgery to improve blood flow. If you are an adult with moyamoya and are scheduled for this surgery, you may be able to help.

This study at Vanderbilt tests whether certain biomarkers (signs in your blood or brain scans) can help tailor care for people with Moyamoya, a condition where blood flow to the brain is reduced. Participants will have brain scans and complete study procedures before and after surgery to improve blood flow.

This trial studies whether a treatment called RIC (remote ischemic conditioning) is safe and helpful for children with moyamoya disease who undergo revascularization surgery. It aims to improve outcomes after surgery and reduce risk, while carefully tracking safety.

This trial tests whether a daily aspirin regimen combined with a blood-pressure cuff treatment on the arm can slow the progression of mild moyamoya disease. It aims to reduce the risk of strokes and bleeding events.

This trial follows people with moyamoya disease who are treated with medication only, and it also looks at first-degree relatives. The goal is to understand long-term outcomes and whether careful conservative care is beneficial over time.

This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.