Testing a new drug combination for advanced gallbladder cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of two chemotherapy drugs (gemcitabine and nab-paclitaxel) with two immunotherapy drugs (iparomlimab and tuvorilimab) for people with advanced gallbladder cancer that cannot be removed by surgery. The goal is to see if this combination can help shrink the cancer or slow its growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with advanced gallbladder cancer that cannot be completely removed by surgery.
- You are between 18 and 75 years old.
- You are in generally good health, able to care for yourself, and have normal liver function (Child-Pugh class A).
- Your blood counts and kidney function are within certain limits (e.g., adequate white blood cells, platelets, and hemoglobin).
- You have not had any cancer treatment (chemotherapy, radiation, or immunotherapy) in the past year and have no other current cancers (except certain cured ones).
- You are not pregnant or nursing, and agree to use effective contraception during the study and for 3 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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