Comparing two drugs to help pass a ureter stone
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests two medications, mirabegron and tamsulosin, to see which works better for helping a single ureter stone pass without surgery. If you have a stone between 4 and 10 mm in size, are 18-75, and have good kidney function, this study may be for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have a single stone in one ureter, confirmed by a scan like CT, ultrasound, or X-ray.
- Your stone is between 4 mm and 10 mm (roughly the size of a small pea to a bean).
- You have had kidney pain (renal colic) or blood in your urine (hematuria).
- Your kidneys work well (eGFR above 60).
- You do not have a urinary tract infection, more than one stone, or severe kidney swelling.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether L-citrulline (a natural amino acid) or tamsulosin (a common blood pressure medication) helps you pass a small kidney stone stuck in your ureter (the tube from kidney to bladder) without surgery. The goal is to compare which medicine works better and is safer.
This study tests whether two medications—melatonin (a sleep aid) and solifenacin (a bladder-control medicine)—can reduce uncomfortable symptoms from a temporary plastic tube (ureteral stent) placed in your urinary system during kidney stone treatment. The goal is to find out if these drugs help you feel better while the stent is in place.
This trial tests a method called burst wave lithotripsy (BWL) to help doctors assess and treat kidney stones during a planned ureteroscopy procedure. It may help surgeons confirm how well the stone is being broken while you are on the operating table.
This trial tests two medicines (terazosin and tamsulosin) to see which one better reduces discomfort from a ureteral stent placed after stone treatment. If you've recently had a stent placed and have no other major health issues, you may be able to join.
This trial is testing three different medicines to see if they can reduce common symptoms like pain and frequent urination caused by a ureteral stent placed after kidney stone surgery. If you are between 19 and 80 years old and had a stent placed during ureteroscopy, you may be able to join.
This trial tests whether two common medications—tamsulosin and aminophylline—help surgeons access kidney stones more easily during a minimally invasive procedure called retrograde intrarenal surgery (RIRS). The goal is to make the surgery smoother and potentially reduce complications.
Hear when a new Ureteral Calculi trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.