Melatonin and solifenacin for ureteral stent discomfort
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether two medications—melatonin (a sleep aid) and solifenacin (a bladder-control medicine)—can reduce uncomfortable symptoms from a temporary plastic tube (ureteral stent) placed in your urinary system during kidney stone treatment. The goal is to find out if these drugs help you feel better while the stent is in place.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age between 18 and 60 years old
- Recently had or will have a procedure to remove a kidney stone with placement of a single plastic tube (Double-J stent) in one ureter
- Able to read, understand, and complete study questionnaires
- Willing to take study medications and attend follow-up visits
- Not allergic or sensitive to solifenacin (Vesicare) or melatonin
- No history of urine retention problems, narrow-angle glaucoma, or severe liver or kidney disease
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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