Investigation of YN001 for Men with ED and Artery Disease
Part of Heart & circulation, Kidney & urinary, Mental health clinical trials.
This study tests an investigational drug (YN001) for men with mild to moderate erectile dysfunction who also have hardening of the arteries (atherosclerosis) in the heart, brain, or legs. The goal is to see if the drug helps improve erections while being safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had mild to moderate erectile dysfunction for at least 3 months, and a score of 21 or less on the IIEF-5 questionnaire.
- You have a history of heart or blood vessel problems such as coronary artery disease, stroke, or clogged arteries in the neck, arms, or legs.
- You are willing to not father a child or donate sperm during the study and for 3 months after, and to use effective birth control.
- You have not had a stroke in the last 6 months.
- You do not have other conditions that could cause erectile dysfunction (like uncontrolled diabetes, hormone problems, or severe liver or kidney disease).
- You have not used certain erectile dysfunction treatments (like injections or vacuum devices) that you cannot stop during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is for men with diabetes and erectile dysfunction (trouble getting or keeping an erection). It tests the safety and effectiveness of sildenafil (Viagra) in this group. You will be prescribed sildenafil and your results will be tracked to see how well it works and if it is safe.
This study tests two different ways to treat erectile dysfunction (ED): a combination of two commonly used medications (tadalafil and sildenafil) versus a single medication (tadalafil). It aims to see which approach works better and is safe for men with ED.
This study tests a new form of sildenafil (the active ingredient in Viagra) for treating erectile dysfunction in men. It aims to see how well it works and how safe it is, and you'll need to track your progress using a smartphone app.
This study compares three forms of sildenafil — a common erectile dysfunction medication — to see how well the body absorbs them after a high-fat meal. It is an early-stage trial in healthy men to check for safety and how the drugs work.
This trial studies a wearable device designed to help men with erectile dysfunction (trouble getting or keeping an erection). You may be able to take part if you have a willing female partner and you can safely try the device during the study.
This study tests a device called EndoPAT to check how well the blood vessels in your penis are working. It may help doctors better understand erectile dysfunction or low testosterone.
Hear when a new Atherosclerotic Cardiovascular Disease (ASCVD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.