Clinical trials
Atherosclerotic Cardiovascular Disease (ASCVD) clinical trials
Below are recruiting atherosclerotic cardiovascular disease (ascvd) clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Birmingham, AlabamaAges 18 years+ - NCT07332468Recruiting
Smartphone-based heart health program versus usual care
This study tests whether a digital remote management program (using a smartphone) helps people at high risk for heart disease or stroke make healthier lifestyle choices and better manage their medications, compared to usual care. It is for adults 35+ who are not already on advanced heart treatments.
BeijingAges 35 years+ - NCT07241390RecruitingPhase 3
Study of orforglipron for heart and kidney health.
This trial tests if orforglipron can reduce the risk of heart attack, stroke, or kidney failure in people with heart disease or chronic kidney disease.
Bahía BlancaAges 50 years+ - NCT06871514Recruiting
Decision support for managing heart disease risk
This trial tests a decision-support tool to help manage cardiovascular risk in people with established heart or blood vessel disease. It aims to improve treatment plans and outcomes.
AlkmaarAges 40–80 - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Daphne, AlabamaAges 45–99 - NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT05765370Recruiting
LDL cholesterol study in people 75+ with heart or blood vessel disease
This trial studies how to lower “bad” cholesterol (LDL) in people age 75 and older who have already had heart, brain, or leg/blood-vessel problems from blocked arteries. The goal is to see if the approach helps prevent further cardiovascular events (like heart attack or stroke).
Beijing, Beijing MunicipalityAges 75 years+ - NCT06494501RecruitingPhase 3
Preventing heart attacks in middle-aged adults with early plaque
This study tests whether starting cholesterol-lowering treatment early can prevent heart attacks in people aged 30-50 who already have early signs of artery plaque but no history of heart disease.
New York, New YorkAges 30–50 - NCT06541691Recruiting
Aspirin for heart disease patients in polluted air
This study tests if different types of aspirin (coated or chewable) and a special schedule can help people with heart or blood vessel disease when they are exposed to air pollution. If you live in Tehran and have stable heart disease, you may be able to join.
Tehran, Tehran ProvinceAges 18 years+ - NCT06571162Recruiting
Study on LDL cholesterol management for heart disease patients
This study tests whether a clinical pharmacist-led team can help manage LDL cholesterol levels in patients with heart or blood vessel disease. It aims to improve care for people with conditions like coronary artery disease, stroke, or peripheral artery disease.
Salt Lake City, UtahAges 18 years+ - NCT06738381Recruiting
Digital prevention program after heart attack or stroke
This trial tests a digital program (using a smartphone or tablet) to help prevent another heart attack or stroke. It is for people who have already had a heart-related event or have known artery plaque buildup.
Drammen, BuskerudAges 18 years+ - NCT06813911RecruitingPhase 3
Testing pelacarsen for high Lp(a) in heart disease patients
This trial tests a new medicine called pelacarsen for people with very high Lp(a) (a type of cholesterol) and existing heart or blood vessel disease. It aims to see if adding pelacarsen to your current cholesterol treatment can lower your Lp(a) levels further.
Birmingham, AlabamaAges 18–80 - NCT06858332Recruiting
Lp(a) cholesterol in adults with heart and blood vessel disease in Russia
This study looks at levels of a type of cholesterol called Lp(a) in people with certain heart and blood vessel diseases. The goal is to understand how common high Lp(a) is in Russian adults with these conditions.
ChelyabinskAges 18–99 - NCT06930885RecruitingPhase 3
Polypill and colchicine for heart and artery risk
This trial tests a combination pill (polypill) and a medicine called colchicine to see if they can lower the risk of future heart attacks, strokes, or other artery problems. It is for people who already have a history of heart or blood vessel disease.
Maceió, AlabamaAges 45 years+ - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT07487363RecruitingPhase 1/Phase 2
TB-500 for heart health in stable artery disease
This study tests if TB-500 can improve blood markers of cardiovascular health in people with stable artery disease. It is an early-phase trial to see if the drug is safe and shows promise.
Shenzhen, GuangdongAges 40–75 - NCT07542860Recruiting
Comparing two aspirin doses in older heart disease patients
This study compares whether a lower dose of aspirin (50 mg) works as well as a standard dose (100 mg) for older adults who have had heart attacks, strokes, or other heart and blood vessel problems. The goal is to find the safest effective dose to prevent future events.
BeijingAges 60 years+ - NCT07551492RecruitingPhase 3
Testing HRS9531 for heart and blood vessel disease
This study tests whether a new drug called HRS9531 can help people with atherosclerotic cardiovascular disease (hardened arteries affecting the heart and blood vessels). The trial will check if it's safe and effective for managing this condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07581808RecruitingPhase 4
Two cholesterol drugs for heart disease prevention
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
LjubljanaAges 18 years+ - NCT07588256Recruiting
AI Digital Health Platform for High Blood Pressure and Related Conditions
This study uses artificial intelligence and a digital health app to help manage high blood pressure, high cholesterol, diabetes, kidney disease, and heart disease. It aims to help people track their health at home and receive better care recommendations through technology.
New Taipei CityAges Any age - NCT06919302Recruiting
Digital heart health app for heart disease patients
This study tests a digital heart health app combined with lifestyle coaching to help people with heart disease or diabetes manage their cholesterol and overall heart health. It aims to see if the app can improve outcomes for people already taking a statin.
Toronto, OntarioAges 45 years+ - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT07034690RecruitingPhase 4
Better cholesterol control for high-risk patients
This study tests whether an educational program can help people with high cholesterol and heart disease get their LDL cholesterol levels lower. It involves watching online videos and working with your doctor to adjust treatments.
Abu DhabiAges 18–100
Hear when a new Atherosclerotic Cardiovascular Disease (ASCVD) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Atherosclerotic Cardiovascular Disease (ASCVD) trials by city
Studies with a site in or near these metro areas.
Atherosclerotic Cardiovascular Disease (ASCVD) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for atherosclerotic cardiovascular disease (ascvd)?
- Yes. Clin2 currently lists 30 recruiting atherosclerotic cardiovascular disease (ascvd) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atherosclerotic cardiovascular disease (ascvd) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atherosclerotic cardiovascular disease (ascvd) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.