Tofacitinib cream for nail psoriasis study
Part of Bones, joints & muscles, Skin clinical trials.
This study tests a cream containing tofacitinib for treating nail psoriasis. It may be an option if you have nail psoriasis and haven't had success with other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have nail psoriasis on at least one fingernail or toenail.
- You are not taking systemic (whole-body) medication for nail psoriasis, or you have tried it for at least 6 months without good results.
- You are willing to sign consent forms for the study and for using your images.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a cream called roflumilast for people with plaque psoriasis on the body and nail psoriasis. It aims to see if the cream safely improves both skin and nails.
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This trial tests whether adding the drug tofacitinib to standard treatment helps reduce symptoms of oral lichen planus, a chronic inflammatory mouth condition. It is for people with moderate to severe disease who have not taken certain immune-suppressing medicines recently.
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This study compares two systemic medications—methotrexate (a traditional immunosuppressant) and tofacitinib (a newer targeted therapy)—to see which works better for moderate-to-severe plaque psoriasis that hasn't responded well to creams or ointments.
This trial tests the drug tofacitinib in children with juvenile idiopathic arthritis (a type of arthritis that starts before age 18). It looks at whether tofacitinib is a safe and effective treatment for this condition.
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