Tofacitinib for oral lichen planus
Treatments studied
Part of Mouth & dental, Skin clinical trials.
This trial tests whether adding the drug tofacitinib to standard treatment helps reduce symptoms of oral lichen planus, a chronic inflammatory mouth condition. It is for people with moderate to severe disease who have not taken certain immune-suppressing medicines recently.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older with a diagnosis of oral lichen planus.
- Your oral lichen planus is moderate to severe (score of 3 or more on a doctor's scale).
- You have not taken systemic corticosteroids (like prednisone pills) in the last 4 weeks.
- You have not used immune-suppressing drugs (like azathioprine or cyclosporine) in the last month.
- You do not have a history of certain cancers, serious infections, or organ problems.
- You are willing to use effective birth control if you could become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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