Heart treatment for irregular heartbeat after a prior blood clot prevention procedure
Part of Heart & circulation clinical trials.
This trial tests a newer way to treat atrial fibrillation (an irregular heartbeat) in people who have already had a procedure to close off the left atrial appendage, a small pouch in the heart that can collect blood and cause strokes. The treatment uses pulsed field energy to target tissue causing the irregular rhythm, which may be safer than standard approaches.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between the ages of 18 and 75 years.
- You have been diagnosed with atrial fibrillation that causes symptoms.
- You have tried at least one heart-rhythm medication (like flecainide or amiodarone) and it didn't help or you couldn't tolerate it.
- You have not had previous heart surgery on the left upper chamber of the heart.
- You do not have a pacemaker or other implanted heart device.
- Your heart's pumping function is relatively good (more than 40% on an echo) and you do not have severe heart failure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a newer ablation technique called pulsed field ablation to treat atrial fibrillation, a heart rhythm disorder. The goal is to see if this method works well and is safe for patients who need treatment.
This study tests a newer, gentler way to fix irregular heartbeats in people with paroxysmal AF. The treatment uses special energy (pulsed fields) guided by 3D imaging to target the heart tissue causing the problem, and the goal is to restore a normal rhythm with fewer risks.
This trial tests whether pulsed-field ablation (a targeted treatment meant to stop abnormal heart signals) works better than a sham, or “placebo,” ablation. It is for certain people with atrial fibrillation (AF) to see if symptoms and heart rhythm outcomes improve.
This trial tests a new method called pulsed field ablation to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to safely stop AF episodes by targeting specific areas in the heart, and may help people with paroxysmal (coming and going) or persistent AF who haven't had this procedure before.
This study looks at how a new type of heart procedure, called pulsed field ablation, affects the heart's structure in people with persistent atrial fibrillation. It may help doctors understand if this treatment improves heart function over time.
This trial tests a newer treatment called pulsed field ablation (PFA) for people with paroxysmal atrial fibrillation (AF), where the heart's rhythm is irregular and comes and goes on its own within 7 days. The goal is to see if PFA can restore a normal heart rhythm while better protecting the heart's left atrial function, which helps pump blood effectively. If you have AF and medications haven't worked, this could be an option to discuss with your doctor.
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