Medication before surgery to reduce autism-related anxiety in children
Treatments studied
Part of Mental health clinical trials.
This trial tests whether a nose spray given before anesthesia can help children with autism feel calmer and have fewer behavior problems after surgery. It compares two medications, dexmedetomidine and esketamine, to see if they reduce negative post-surgery changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Child is between 2 and 12 years old
- Has a doctor's diagnosis of autism spectrum disorder (ASD)
- Is scheduled for an elective surgery that is not heart, lung, brain, or spine surgery
- Does not have other severe medical conditions like liver or kidney problems
- Has not taken sedatives or pain relievers in the 48 hours before surgery
- Has not had a major life change (like a divorce or move) in the past month
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two medicines given as a nasal spray (dexmedetomidine or esketamine) to see which one better prevents emotional or behavior problems in children after they wake up from surgery. It may help your child feel calmer and avoid changes like crying or confusion after anesthesia.
This trial tests whether a nasal spray with a calming medicine (dexmedetomidine) can reduce anxiety before brain surgery. It is given before the operation to help you feel more relaxed and calm.
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
This trial tests a medicine given as nose drops to help children relax before anesthesia and reduce confusion or agitation after surgery. It may make the anesthesia experience smoother for young children having minor surgeries.
This trial compares two safe, common ways to help children relax before surgery: a medicine sprayed in the nose versus a medicine given by mouth. The goal is to see which one works better and is easier for kids.
This study compares two sedative medicines given as a nasal spray to help children relax and reduce separation anxiety before surgery. It aims to find which medicine works better for children aged 2 to 6.
Hear when a new Autism spectrum disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.