Medication before surgery to reduce autism-related anxiety in children
Treatments studied
Part of Mental health clinical trials.
This trial tests whether a nose spray given before anesthesia can help children with autism feel calmer and have fewer behavior problems after surgery. It compares two medications, dexmedetomidine and esketamine, to see if they reduce negative post-surgery changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Child is between 2 and 12 years old
- Has a doctor's diagnosis of autism spectrum disorder (ASD)
- Is scheduled for an elective surgery that is not heart, lung, brain, or spine surgery
- Does not have other severe medical conditions like liver or kidney problems
- Has not taken sedatives or pain relievers in the 48 hours before surgery
- Has not had a major life change (like a divorce or move) in the past month
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether a nasal spray medication given after surgery can help prevent negative behavior changes (like anxiety or clinginess) that sometimes happen in children after anesthesia. Researchers will compare two different medications to see which works better.
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This trial tests a nasal spray medicine called dexmedetomidine to help children relax before surgery and reduce agitation after waking up. It also monitors brain activity during anesthesia to ensure safety and effectiveness.
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