Exercise and irisin levels in axial spondyloarthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This trial tests whether a specific exercise program can improve symptoms and increase irisin (a protein linked to metabolism and inflammation) in people with active axial spondyloarthritis (a type of inflammatory arthritis affecting the spine and joints). It may help you if you have moderate-to-severe disease and have not been very active recently.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have axial spondyloarthritis diagnosed by a rheumatologist.
- Your disease is currently active (score above 2.1 on a standard severity test).
- You have not been exercising regularly (less than 3 days a week) for the past 3 months.
- Your medication for ankylosing spondylitis has not changed in the last 3 months.
- You are between 18 and 50 years old.
- Your body mass index (BMI) is 25 or less.
- You do not have any heart, lung, bone, nerve, or mental health problems that would make exercise unsafe.
- You do not use a walker, cane, or other aid to walk.
- You are not pregnant.
- You have no recent history of cancer or surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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