Combined therapy for severe pneumonia from resistant bacteria
Treatments studied
Part of Infections, Lungs & breathing clinical trials.
This trial tests whether adding a Chinese herbal formula (Yiqi Huoxue Jiedu) and inhaled bacteriophages (viruses that kill bacteria) to standard care can help treat severe pneumonia caused by drug-resistant bacteria like Klebsiella, Acinetobacter, or Pseudomonas. It is for adults aged 18 to 85 who are not pregnant or immunocompromised and can undergo a bronchoscopy to collect samples.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 85 years old.
- You have severe pneumonia caused by a drug-resistant Gram-negative bacterium (such as Klebsiella, Acinetobacter, or Pseudomonas).
- You are willing to have a bronchoscopy with bronchoalveolar lavage to collect lung samples.
- You agree to receive inhaled bacteriophage therapy via a nebulizer.
- You are not pregnant, breastfeeding, or have a weakened immune system.
- You have not been on a breathing machine for more than 60 days before joining the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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