Cancer vaccine trial for pseudomyxoma peritonei
Treatments studied
Part of Cancer clinical trials.
This trial tests a vaccine for people with a rare abdominal cancer called pseudomyxoma peritonei (PMP) that has come back or cannot be removed by surgery. The vaccine is designed to help the immune system fight the cancer. It is for people whose tumor has a specific genetic change (GNAS mutation) and who have no other standard treatment options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You must have pseudomyxoma peritonei (PMP) that has come back or cannot be removed, and no other treatments expected to work.
- Your tumor must have a specific genetic change called a GNAS mutation.
- You must be well enough to have small tissue samples (biopsies) taken from the tumor in your abdomen.
- Your blood counts, kidney function, and liver function must be within certain safe levels.
- You must be able to care for yourself (ECOG score of 0 or 1).
- You must not be pregnant or breastfeeding, and you must use effective birth control during the study and for 6 months after.
- You cannot have other active cancers (except some minor skin or cervical cancers), active infections like hepatitis or HIV, or autoimmune diseases that could flare up.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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