Intestinal transplant for extensive mucinous abdominal cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests if an intestinal or multi-organ transplant can help people with a rare, widespread abdominal cancer called pseudomyxoma peritonei that cannot be removed by standard surgery. The goal is to remove all visible cancer and replace affected organs with a donated transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with pseudomyxoma peritonei (a rare abdominal cancer).
- Your cancer is widespread in the abdomen and cannot be completely removed with standard surgery.
- The cancer has not spread outside your abdomen, except possibly to the lungs.
- You are between 18 and 75 years old.
- You are well enough to have a major surgery and can walk and care for yourself (ECOG score 0 or 1).
- You have no other treatment options that could cure your cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a chemotherapy combination (capecitabine and cyclophosphamide) given before surgery for people with a large amount of pseudomyxoma peritonei (PMP). The goal is to see if it can shrink the tumor and make surgery more effective.
This trial tests a vaccine for people with a rare abdominal cancer called pseudomyxoma peritonei (PMP) that has come back or cannot be removed by surgery. The vaccine is designed to help the immune system fight the cancer. It is for people whose tumor has a specific genetic change (GNAS mutation) and who have no other standard treatment options.
This trial compares two different schedules of heated chemotherapy (HIPEC) after surgery for pseudomyxoma peritonei (a rare appendix cancer that spreads in the abdomen). It may help determine whether one or three cycles of HIPEC is better for controlling the disease.
This trial tests whether the drug metformin (a common diabetes pill) can help control pseudomyxoma peritonei, a rare abdominal cancer. It is for people whose cancer has come back or cannot be surgically removed, and who aren't planning a major surgery with heated chemotherapy at this time.
This trial compares a lower dose of heated chemotherapy (HIPEC) given during surgery to a standard dose for patients with pseudomyxoma peritonei (a condition where jelly-like mucus builds up in the abdomen). The goal is to see if the lower dose works just as well with fewer side effects.
This study tests if giving patients a stool transplant (also called FMT) in capsules along with their first chemotherapy can help treat advanced pancreatic cancer that cannot be removed by surgery.
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