Ultrasound and Immunotherapy for Newly Diagnosed Brain Cancer
Part of Cancer clinical trials.
This trial tests whether a special ultrasound (LIFU) can open the blood-brain barrier to help an immunotherapy drug (cetuximab) reach glioblastoma tumors better. It is for people with a specific type of glioblastoma that has not been treated yet and that has a certain protein called EGFR.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of brain tumor called glioblastoma (or gliosarcoma) that is newly diagnosed, has not spread to other parts of the body, and has a protein called EGFR.
- The tumor is in part of the brain that is safe to treat with the ultrasound device, and at least 30 mm away from the skull.
- After your surgery, the remaining tumor seen on MRI is 2 cm³ or less.
- You are between 18 and 70 years old.
- Your overall health (Karnofsky score) is 70 or higher, meaning you can take care of yourself.
- You must be able to talk with the ultrasound team during the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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