Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is between 3 and 7 years old
- Your child is scheduled for surgery to remove tonsils and/or adenoids (adenotonsillectomy) under general anesthesia
- Your child is generally healthy or has only a mild health condition (classified as ASA I or II)
- You are willing for your child to participate and can give consent
- Your child does not have a known allergy to melatonin, dexmedetomidine, or midazolam
- Your child does not have a developmental delay, intellectual disability, or certain neurological or psychiatric conditions (like cerebral palsy, epilepsy, or ADHD)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a medication given through the nose (dexmedetomidine) can help children stay calmer when waking up from eye-muscle surgery. Some children get very agitated or upset when coming out of anesthesia, and this medication might help prevent that.
This trial tests if giving magnesium through the mouth works as well as through the vein to prevent confusion or agitation right after surgery in children having their tonsils out. It aims to find a simpler way to help kids wake up calmly.
This study compares two medicines to see which works better at preventing agitation and restlessness when children wake up from surgery with a common anesthetic. The goal is to help children recover more calmly and comfortably.
This trial tests a medicine given as nose drops to help children relax before anesthesia and reduce confusion or agitation after surgery. It may make the anesthesia experience smoother for young children having minor surgeries.
This study looks at whether giving a sedative (midazolam) earlier or later before surgery affects stress and recovery in children having their tonsils and/or adenoids removed. It may help reduce anxiety and improve recovery after surgery.
This study tests adding a medicine called dexmedetomidine to a numbing injection near the cheekbone to see if it improves pain control for children having their tonsils partially removed. It aims to make recovery more comfortable and reduce breathing problems after surgery.
Hear when a new Emergence Agitation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.