Colchicine for non-severe coronary plaque: a trial
Part of Heart & circulation clinical trials.
This trial tests if the anti-inflammatory drug colchicine can help people with non-severe coronary artery plaque seen on a CT scan. It may be an option if you have stable chest pain or related symptoms and your heart arteries are partly blocked but not severely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with chronic coronary syndrome (stable chest pain or related symptoms).
- A CT scan shows at least 50% narrowing in one heart artery, but a special CT measurement (CT-FFR) shows it's not severely blocking blood flow (value above 0.80).
- You have not had a heart stent in the last 3 months or bypass surgery.
- You do not have inflammatory bowel disease, stomach ulcers, or other conditions listed that would make colchicine unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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