Testing anti-inflammatory therapy in high-risk coronary disease
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether adding a targeted anti-inflammatory drug to standard care can prevent future heart attacks or strokes in people with high-risk chronic coronary artery disease. It is for people who have a moderate narrowing in a heart artery with a vulnerable plaque and signs of inflammation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 90 years old.
- You have had a prior heart attack, stroke, or peripheral artery disease, or you have diabetes, or a high estimated risk of heart attack or stroke.
- You have a moderate narrowing (30-80%) in at least one heart artery with a specific type of vulnerable plaque, and a blood test showing inflammation (hs-CRP > 2).
- You have been taking a stable dose of a statin medication for at least 4 weeks.
- You are not pregnant, do not have severe kidney or liver disease, severe heart failure, recent heart attack, or unstable angina.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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