Study of esketamine plus pregabalin and duloxetine for shingles nerve pain
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This trial tests whether adding esketamine to two standard pain medicines (pregabalin and duloxetine) can better treat nerve pain from shingles that persists for months. It's for people whose pain hasn't improved enough with pregabalin alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have nerve pain from shingles that has lasted more than 3 months after the rash healed
- Your average pain score is at least 4 out of 10 on a standard pain scale
- You have tried pregabalin alone without enough relief or couldn't tolerate it
- You do not have certain health conditions like sleep apnea, severe organ problems, or a history of drug abuse
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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